Batch
Feb 26
Purity
99.24%
Tested

Gold Tier

Retatrutide

GLP-3

Research-use-only next-gen triple agonist GLP peptide engaging GLP-1, GIP, and Glucagon pathways. Studied in bioenergetic models of appetite, glucose handling, and multi-receptor metabolic signaling.

  • Assesses multi-pathway energy signaling.
  • Explores stress-adaptive metabolism.
  • ≥99% Pure | 5X Tested | PhD-Formulated | GMP/ISO

In stock

Price range: $120.00 through $225.00

Latest certificate on record

Batch Feb 26 · Apex Labs

View certificate of analysis

Description

GLP-3 | Introduction

GLP-3 is a research-use-only, triple agonist incretin-pathway analog engaging GLP-1 + GIP + Glucagon receptors. Investigations probe multi-receptor signaling integration, mitochondrial efficiency, and redox-sensitive responses in vitro. Not intended for diagnostic or therapeutic use.

      • Triple-receptor incretin/glucagon signaling models
      • Energy balance and metabolic stress studies
      • Redox and mitochondrial efficiency assessments

Latest Certificate of Analysis.

View COA history.

NameGLP-3 Research Analog (Triple GLP-1 + GIP + Glucagon Agonist)
SynonymsTriple incretin/glucagon analog | GLP-1/GIP/GCGR co-agonist
Sequence39-aa peptide with lipidation; KEGG motif: YXQGTFTSDY SILLDKKAQX AFIEYLLEGG PSSGAPPPS (X = non-canonical residue)
Molecular FormulaC221H342N46O68
Molecular Weight≈4731.34 g/mol (free base)
CAS Number2381089-83-2
AppearanceWhite to off-white lyophilized powder
SolubilitySoluble in sterile water or bacteriostatic water
Purity≥99% (HPLC)
Storage Guidelines• Lyophilized: ≤0°F (–18°C), dry, protected from light
• Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw
• Long-Term: Keep dry and frozen until use
  • Purity & Identity: ≥99% | HPLC & MS validated
  • Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
  • Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
  • Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
  • Packaging: Luxe Fridge-Ready Box

Bioenergetic peptides are used in RUO studies to explore how cells generate, manage, and recover energy. These compounds interact with key metabolic pathways—especially mitochondrial ATP output and redox signaling—making them essential tools for researchers investigating energy dysfunction, oxidative stress, and cell viability under stress conditions.

Exciting Areas of Study

  • Modulation of ATP output in energy-restricted cellular environments
  • Pre-clinical insights into mitochondrial performance
  • Stress-induced metabolic pathway behavior in controlled assays
  • Early-stage models of energy dysregulation across tissue types
  • Insulin sensitivity & glucose regulation in cell-based assays
  • Characterize triple-receptor signaling vs. metabolic outputs
  • Evaluate stress-adaptive energy regulation
  • Benchmark responses against single/dual incretin models

This product is intended solely for laboratory research purposes. It is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and our Research Compliance Disclaimers for details.

Additional information

Select Strength (MG)

10MG, 20MG, 30MG, 40MG

Lab Results & Certificates

BatchTest dateLaboratoryTypeCertificate
Feb 2622 Sep 2026Apex LabsCertificate of Analysis

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Knowledge Hub

Research & Education

Guides and reference material related to Retatrutide.

  • Compound Guide

    Retatrutide (GLP-1 / GIP / Glucagon Tri-Agonist): Molecular Mechanisms & Preclinical Findings

    An in-depth biochemical review of Retatrutide (LY3437943), examining its multi-target agonist activity at GLP-1, GIP, and glucagon receptors, downstream cAMP accumulation, and energetic homeostasis in laboratory research models.

    Compound
    Retatrutide
    Last reviewed
    Revision
    1.2
    Read guide: Retatrutide (GLP-1 / GIP / Glucagon Tri-Agonist): Molecular Mechanisms & Preclinical Findings
  • Testing / COA Education

    Reading Lab Certificates of Analysis (COA): HPLC Traces & Mass Spectrometry

    A practical guide to interpreting analytical test reports: deciphering RP-HPLC chromatograms, understanding baseline integration, verifying electrospray ionization (ESI-MS) molecular mass, and evaluating third-party lab verification.

    Compound
    Retatrutide, mots-c
    Last reviewed
    Revision
    1.0
    Read guide: Reading Lab Certificates of Analysis (COA): HPLC Traces & Mass Spectrometry
  • Handling / Storage

    Peptide Reconstitution & Storage: Preserving Lyophilized Cake Stability

    Essential laboratory guidelines for reconstituting lyophilized peptides: selecting diluents, minimizing shear stress during fluid introduction, temperature cycling parameters, and optimal freeze-thaw mitigation.

    Last reviewed
    Revision
    2.0
    Read guide: Peptide Reconstitution & Storage: Preserving Lyophilized Cake Stability

Browse the Knowledge Hub

  • Testing / COA Education

    Reading Lab Certificates of Analysis (COA): HPLC Traces & Mass Spectrometry

    A practical guide to interpreting analytical test reports: deciphering RP-HPLC chromatograms, understanding baseline integration, verifying electrospray ionization (ESI-MS) molecular mass, and evaluating third-party lab verification.

    Compound
    Retatrutide, mots-c
    Last reviewed
    Revision
    1.0
    Read guide: Reading Lab Certificates of Analysis (COA): HPLC Traces & Mass Spectrometry
  • Handling / Storage

    Peptide Reconstitution & Storage: Preserving Lyophilized Cake Stability

    Essential laboratory guidelines for reconstituting lyophilized peptides: selecting diluents, minimizing shear stress during fluid introduction, temperature cycling parameters, and optimal freeze-thaw mitigation.

    Last reviewed
    Revision
    2.0
    Read guide: Peptide Reconstitution & Storage: Preserving Lyophilized Cake Stability
  • Comparison

    Wolverine 20: BPC-157 & TB-500 Synergistic Tissue Repair Pathways

    Examining the multi-modal angiogenic and cellular migration dynamics when pairing stable gastric pentadecapeptide BPC-157 with actin-sequestering peptide TB-500 in tissue culture and connective tissue assays.

    Compound
    bpc-157, tb-500
    Last reviewed
    Revision
    1.1
    Read guide: Wolverine 20: BPC-157 & TB-500 Synergistic Tissue Repair Pathways
  • Compound Guide

    Retatrutide (GLP-1 / GIP / Glucagon Tri-Agonist): Molecular Mechanisms & Preclinical Findings

    An in-depth biochemical review of Retatrutide (LY3437943), examining its multi-target agonist activity at GLP-1, GIP, and glucagon receptors, downstream cAMP accumulation, and energetic homeostasis in laboratory research models.

    Compound
    Retatrutide
    Last reviewed
    Revision
    1.2
    Read guide: Retatrutide (GLP-1 / GIP / Glucagon Tri-Agonist): Molecular Mechanisms & Preclinical Findings

Lab Results & Certificates

BatchTest dateLaboratoryTypeCertificate
Feb 2622 Sep 2026Apex LabsCertificate of Analysis